產(chǎn)品編號	英文名稱	CAS號	包裝
Y3744	Rosmarinic acid	20283-92-5	可根據(jù)客戶要求訂制

產(chǎn)品編號：Y3744

英文名稱：Rosmarinic acid
CAS號：20283-92-5
分析標(biāo)準(zhǔn)品,≥97%
分子式 C18H16O8 分子量360.31

基本信息:

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熔點(diǎn) 171-175°C
溶解性 Soluble in water (100 mM), ethanol (~25 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (pH 7.2) (~15 mg/ml).
描述
別名 迷迭香酸;(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
生化機(jī)理 Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35.
應(yīng)用 An activator of GPR35.